Hutchinson-Guilford sindrom

Hutchinson-Guilford sindrom opisali su Jonathan Hutchinson 1886. godine i Hastings Guilford 1904. godine. Trenutno u svijetu ima svega 30-tak oboljelih. Koža ovih bolesnika bora se tako brzo da već mala djeca izgledaju kao starci, a svi umiru prije 20-te godine života. Simptomi i znakovi bolesti uključuju: brzo boranje kože, generaliziranu alopeciju, mali rast, distrofične nokte, usporeno spolno sazrijevanje, karakteristično povećanu ekskreciju hijaluronske kiseline i smanjenu mitotičku aktivnost većine tkiva. Od 6300 do sada pretraženih gena nadeno je 76 mutiranih (15 od njih uključeni su u regulaciju staničnog ciklusa pri mitozi, a od ostalih za fenotip su vjerojatno važne mutacije gena za dezmoplakin-1, mali proteoglikan što se veže za kolagene i gena za galaktozil-transferazu).


Hutchinson-Guilford sindrom

DO GREYS HAVE PROGERIA ?

Among humans, Hutchinson-Gilford Syndrome, often called "Progeria," has a very low incidence. On Earth it occurs about once in about every four to eight million births. Very little is known about what causes progeria, but it is thought to be a genetic disease, the result of a spontaneous mutation in the sperm or egg.



Many of the symptoms of progeria seemingly occur among a race of reported "aliens", namely those humanoids referred to as the "Greys." Greys are most often reported to abduct humans , but also surface in reports of bodies associated with UFO crashes. Most UFO abductees, without realizing it, report physical symptoms of progeria among these aliens. This is very interesting, considering that the majority of UFO abductees are not paediatricians specialising in progeria, and it is even more interesting, considering that most doctors rarely ever see progeria patients in their careers.